Diana Cruz, PhD -Computational Biologist
Diana Cruz, PhD - Computational Biologist at Haya Therapeutics
Where are you from, and what is your educational background?
I am Mexican, and my background is in Genomics and Computational Biology. My academic journey started with a Genomics undergrad at UNAM in Mexico, followed by an MSc in Bioinformatics and Computational Biology at the University of Bern, and finally a PhD in Life Sciences at the University of Lausanne.
My research focused on ancient DNA, exploring both the technical challenges of working with this material and its applications in understanding human population evolution and the spread of ancient pathogens.
Why did you decide to pursue the PhD path?
A combination of factors led me to pursue a PhD. My prior research experience, including first-author publications, ignited my passion for research. Furthermore, the chance to contribute to the understudied area of ancient genomics in the Americas felt like a unique and important opportunity. My master's supervisor's projects in this area were a key inspiration, so I decided to stay in Switzerland for my PhD.
When did you realize that you didn’t want to pursue an academic career?
Although I thoroughly enjoyed my PhD research, I realized during the process that I was increasingly drawn to a career with a more direct, tangible impact. The pandemic then kicked in, and I kept thinking that I could translate my hard skills and knowledge in Genomics and Computational Biology to solve real-world problems.
When did you transition into industry, and with which company?
I transitioned into industry in 2023, joining HAYA Therapeutics as an intern after completing my PhD.
What is your current position, and what do you do?
I'm currently a Computational Biologist at HAYA Therapeutics. My role involves analyzing complex biological data using high-performance computing to solve critical challenges in this process.
Was transitioning into industry your only plan, or did you have other fields in mind?
Not really. I also explored opportunities in NGOs and public sector research. Ultimately, the majority of research-oriented positions that aligned with my skills and experience were within the industry at the time I was out in the job market.
Is your job related to the work you did during your PhD?
While the specific research focus has shifted, my current role leverages many of the skills I developed during my PhD. These include independent research design, a strong foundation in biology/genomics and statistics, and the ability to analyze large datasets using high-performance computers to answer complex questions. However, a significant shift from my PhD is the emphasis on team-based projects. My current role requires constant communication and coordination with multiple teams in order to achieve shared goals.
What aspects of your job do you enjoy the most?
Professional and personal growth, by far. Reflecting on how much I've learned and grown since my first day is truly gratifying. Being actively involved in building new therapies provides an invaluable, comprehensive view of the drug development process. The opportunity to test new ideas and contribute to the development of new treatments is incredibly motivating. And, of course, working alongside such a talented team makes all the difference!
How did you adapt to the cultural and operational differences between academia and your current role?
I've found that structured note-taking and prioritizing tasks, which I was already practicing during my PhD, has become even more crucial for staying aligned in a fast-paced environment. Similarly, while I was already learning the importance of clear communication, I've had to become even more proactive in asking questions to ensure everyone is on the same page and moving forward with our goals. I have to admit that I needed to get out of my comfort zone, since I tend to think that I might disturb my colleagues by asking them questions; on the contrary, this helps us bring clarity and re-assess our strategy if needed, instead of sticking to a plan with little chance of succeeding.
As a non-EU citizen, what was your experience transitioning from your PhD to your first position outside academia? What challenges did you face during this transition?
Transitioning from my PhD to a position outside academia as a non-EU citizen presented a significant set of challenges. Despite beginning my job search well in advance of graduation, I faced repeated challenges related to my temporary permit status. The six-month validity period, coupled with the time required for permit renewal and the need for employer-sponsored work permits, created a complex landscape. Several interviewers were transparent about their need for immediate hires, which unfortunately limited my options. The BNF program proved to be a turning point, but even accessing this valuable resource was challenging. Navigating the administrative requirements and conflicting information about my eligibility, all while facing a rapidly approaching permit expiration, created a very stressful situation. I had an extremely narrow window to secure an internship through the BNF program. I'm incredibly relieved that everything worked out in the end, and I'm deeply appreciative of my company's flexibility and support in onboarding me so quickly.
What helped you succeed in your career transition?
Cultivating a growth mindset and embracing the idea that my PhD skills were transferable and valuable in different career paths. The career events and workshops offered by UNIL were instrumental in this process, providing valuable insights and helping me recognize my readiness for new challenges. I attended these events early in my PhD, which allowed me to gradually prepare for my career transition through consistent, small steps.
What advice made the most difference in your professional development?
The simplest advice is the best one. For instance, a reminder that a fulfilling and successful career is possible outside of academia. This was particularly important for me given the ups and downs I would face during my PhD. Someone reassured me that I could build a rewarding career in any field, as long as I prioritized finding a supportive and collaborative work environment. This advice instilled in me the confidence to explore new paths and ultimately led me to seek out a company where I would find a truly supportive and fulfilling work experience.
What advice would you give to PhDs and postdocs seeking opportunities in your field?
For a career in R&D, continuously update your knowledge with the latest technological advancements in your field. Staying informed will not only make you a more competitive candidate but also equip you with the skills and knowledge to excel in a rapidly evolving field.
Recognize that academic environments can sometimes be challenging. If you're facing a difficult situation, remember that you have the power to shape your own career path. Focus on developing your unique skills and strengths, and cultivating a growth mindset! This will greatly help you be ready for the next steps.
It’s often said that networking plays a crucial role in professional transitions. Was this true for you?
Networking is an ongoing process that requires consistent effort. Through active networking, I was able to expand my professional network, attend industry events, and connect with professionals in my field. These experiences led to several opportunities, such as teaching and mentoring roles, which not only enriched my CV but also provided me with professional development. It is hard to quantify the actual impact of networking, but it has provided me with an invaluable network of mentors and prepared me for the collaborative environment I now thrive in.
If you could go back, would you change anything about your career path?
I would have explored opportunities for industry internships during my PhD more actively. Unfortunately, my non-EU citizenship status presented some limitations in this regard. Looking back, I also believe that pursuing a PhD research topic with more direct industrial applications could have further streamlined my career transition.
What can I wish you for the years to come?
Not specifically for me, but for society in general: close the pay gap!
Diana’s LinkedIn: https://www.linkedin.com/in/dicd/
